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The PPPY Motif of Human T-Cell Leukemia Virus Type 1 Gag Protein Is Required Early in the Budding Process

Domains required late in the virus budding process (L domains) have been identified in the Gag proteins of a number of retroviruses. Here we show that the human T-cell leukemia virus type 1 candidate L domain motif PPPY is indeed required for virus production. Strikingly, however, mutation of this m...

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Udgivet i:J Virol
Principais autores: Le Blanc, Isabelle, Prévost, Marie-Christine, Dokhélar, Marie-Christine, Rosenberg, Arielle R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12208980/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.19.10024-10029.2002
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