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Plasma hydroxy-metronidazole/metronidazole ratio in patients with liver disease and in healthy volunteers.

Metronidazole pharmacokinetics were studied in patients with different degrees of liver cirrhosis, classified according to the Child-Pugh algorithm (A, B or C, as liver disease severity increases) and in schistosomic patients. Metronidazole (500 mg) was administered i.v. as a slow infusion over 20 m...

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Detalhes bibliográficos
Main Authors: Muscará, M N, Pedrazzoli, J, Miranda, E L, Ferraz, J G, Hofstätter, E, Leite, G, Magalhães, A F, Leonardi, S, De Nucci, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365194/
https://ncbi.nlm.nih.gov/pubmed/8703652
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