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Relationship between SU Subdomains That Regulate the Receptor-Mediated Transition from the Native (Fusion-Inhibited) to the Fusion-Active Conformation of the Murine Leukemia Virus Glycoprotein

Envelope glycoproteins (Env) of retroviruses are trimers of SU (surface) and TM (transmembrane) heterodimers and are expressed on virions in fusion-competent forms that are likely to be metastable. Activation of the viral receptor-binding domain (RBD) via its interaction with a cell surface receptor...

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Autors principals: Lavillette, Dimitri, Ruggieri, Alessia, Boson, Bertrand, Maurice, Marielle, Cosset, François-Loïc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC136517/
https://ncbi.nlm.nih.gov/pubmed/12208946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9673-9685.2002
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