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Absorption of clonazepam after intranasal and buccal administration.

Serum concentrations of clonazepam after intranasal, buccal and intravenous administration were compared in a cross-over study in seven healthy male volunteers. Each subject received a 1.0 mg dose of clonazepam intranasally and buccally and 0.5 mg intravenously. A Cmax of 6.3 +/- 1.0 ng ml-1 (mean;...

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Autors principals: Schols-Hendriks, M W, Lohman, J J, Janknegt, R, Korten, J J, Merkus, F W, Hooymans, P M
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365135/
https://ncbi.nlm.nih.gov/pubmed/7640154
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