Pregenomic RNA Is Required for Efficient Incorporation of Pol Polyprotein into Foamy Virus Capsids

The foamy virus (FV) Pol polyprotein is translated independently of Gag from a spliced mRNA. This method of expression raises the question of how Pol is associated with the viral particle. Using a transient FV vector transfection system, it is shown that pregenomic RNA is required for efficient viri...

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Bibliographic Details
Main Authors: Heinkelein, Martin, Leurs, Cordula, Rammling, Matthias, Peters, Katrin, Hanenberg, Helmut, Rethwilm, Axel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC136505/
https://ncbi.nlm.nih.gov/pubmed/12208988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.10069-10073.2002
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