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Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in patients with the acquired immunodeficiency syndrome.

1. Zidovudine (ZDV) has proved unsuccessful in controlling disease progression over extended periods of time in patients with AIDS. Combination of ZDV with another reverse transcriptase inhibitor, dideoxyinosine (ddI) may improve the duration of effectiveness of antiretroviral therapy. The aim of th...

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Bibliographic Details
Main Authors: Barry, M, Howe, J L, Ormesher, S, Back, D J, Breckenridge, A M, Bergin, C, Mulcahy, F, Beeching, N, Nye, F
Format: Artigo
Language:Inglês
Published: 1994
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364896/
https://ncbi.nlm.nih.gov/pubmed/8054247
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