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Large-Scale, pH-Dependent, Quaternary Structure Changes in an RNA Virus Capsid Are Reversible in the Absence of Subunit Autoproteolysis

The assembly and maturation of the coat protein of a T=4, nonenveloped, single-stranded RNA virus, Nudaurelia capensis ω virus (NωV), was examined by using a recombinant baculovirus expression system. At pH 7.6, the coat protein assembles into a stable particle called the procapsid, which is 450 Å i...

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Detalhes bibliográficos
Main Authors: Taylor, Derek J., Krishna, Neel K., Canady, Mary A., Schneemann, Anette, Johnson, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136487/
https://ncbi.nlm.nih.gov/pubmed/12208973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.19.9972-9980.2002
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