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Mixed linear and non-linear disposition of lazabemide, a reversible and selective inhibitor of monoamine oxidase B.

1. Single oral doses (100-300 mg) and multiple oral doses (100-350 mg 12 hourly for 7 days) of lazabemide were administered to 35 young and 40 elderly healthy subjects. Plasma concentrations of unchanged drug were determined to study the dose-concentration relationship. 2. The elimination phase time...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guentert, T W, Holford, N H, Pfefen, J P, Dingemanse, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364813/
https://ncbi.nlm.nih.gov/pubmed/7917772
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