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Dose of midazolam should be reduced during diltiazem and verapamil treatments.

1. The effects of diltiazem and verapamil on the pharmacokinetics and pharmacodynamics of midazolam were investigated in a double-blind randomized cross-over study of three phases. 2. Nine healthy volunteers were given orally diltiazem (60 mg), verapamil (80 mg) or placebo three times daily for 2 da...

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Detalhes bibliográficos
Main Authors: Backman, J T, Olkkola, K T, Aranko, K, Himberg, J J, Neuvonen, P J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364750/
https://ncbi.nlm.nih.gov/pubmed/8198928
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