Cigarette smoking enhances the elimination of quinine.

The pharmacokinetics of a single dose (600 mg) of quinine sulphate were examined in a group of non-smokers (n = 10) and in heavy cigarette smokers (n = 10). The mean (+/- s.d.) oral clearance of quinine in smokers (0.189 +/- 0.075 1 h(-1) kg(-1)) was significantly greater than in non-smokers (0.107...

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Detalhes bibliográficos
Main Authors: Wanwimolruk, S, Wong, S M, Coville, P F, Viriyayudhakorn, S, Thitiarchakul, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364670/
https://ncbi.nlm.nih.gov/pubmed/12959282
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