The Immunogenicity and Protective Efficacy of Bovine Herpesvirus 1 Glycoprotein D plus Emulsigen Are Increased by Formulation with CpG Oligodeoxynucleotides

The immunogenicity and protective efficacy of a bovine herpesvirus 1 (BHV-1) subunit vaccine formulated with Emulsigen (Em) and a synthetic oligodeoxynucleotide containing unmethylated CpG dinucleotides (CpG ODN) was determined in cattle. A truncated, secreted version of BHV-1 glycoprotein D (tgD) f...

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Détails bibliographiques
Auteurs principaux: Ioannou, X. P., Griebel, P., Hecker, R., Babiuk, L. A., van Drunen Littel-van den Hurk, S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC136463/
https://ncbi.nlm.nih.gov/pubmed/12186884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9002-9010.2002
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