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Absorption and in vivo dissolution of hydroxycholoroquine in fed subjects assessed using deconvolution techniques.
1. Nine healthy subjects each received three doses of 155 mg rac-hydroxychloroquine, as a tablet, an oral solution and by intravenous infusion, in a randomised cross-over design study, 30 min after a standard high fat breakfast. 2. Four methods of deconvolution were used to assess the absolute bioav...
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Huvudupphovsmän: | , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
1993
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1364612/ https://ncbi.nlm.nih.gov/pubmed/12959287 |
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