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Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

Hepatitis C virus (HCV) sets up a persistent infection in patients that likely involves a complex virus-host interaction. We previously found that the HCV nonstructural 5A (NS5A) protein interacts with growth factor receptor-binding protein 2 (Grb2) adaptor protein and inhibits the activation of ext...

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Published in:J Virol
Main Authors: He, Yupeng, Nakao, Haruhisa, Tan, Seng-Lai, Polyak, Stephen J., Neddermann, Petra, Vijaysri, Sangeetha, Jacobs, Bertram L., Katze, Michael G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136456/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12186904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.18.9207-9217.2002
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