Potent and Specific Inhibition of Human Immunodeficiency Virus Type 1 Replication by RNA Interference

Synthetic small interfering RNAs (siRNAs) have been shown to induce the degradation of specific mRNA targets in human cells by inducing RNA interference (RNAi). Here, we demonstrate that siRNA duplexes targeted against the essential Tat and Rev regulatory proteins encoded by human immunodeficiency v...

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Bibliographische Detailangaben
Hauptverfasser: Coburn, Glen A., Cullen, Bryan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136455/
https://ncbi.nlm.nih.gov/pubmed/12186906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9225-9231.2002
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