Interaction of the Vp3 Nuclear Localization Signal with the Importin α2/β Heterodimer Directs Nuclear Entry of Infecting Simian Virus 40

For nuclear entry of large nucleoprotein complexes, it is thought that one key nuclear localization signal (NLS) of a protein component becomes exposed to mediate importin recognition. We show that the nuclear entry of simian virus 40 involves a dynamic interplay between two distinct interiorly situ...

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Detalhes bibliográficos
Main Authors: Nakanishi, Akira, Shum, Dorothy, Morioka, Hiroshi, Otsuka, Eiko, Kasamatsu, Harumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136453/
https://ncbi.nlm.nih.gov/pubmed/12186919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9368-9377.2002
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