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Induction of Immune Responses in Mice and Monkeys to Ebola Virus after Immunization with Liposome-Encapsulated Irradiated Ebola Virus: Protection in Mice Requires CD4(+) T Cells

Ebola Zaire virus (EBO-Z) causes severe hemorrhagic fever in humans, with a high mortality rate. It is thought that a vaccine against EBO-Z may have to induce both humoral and cell-mediated immune responses to successfully confer protection. Because it is known that liposome-encapsulated antigens in...

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Detalles Bibliográficos
Main Authors: Rao, Mangala, Bray, Mike, Alving, Carl R., Jahrling, Peter, Matyas, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136452/
https://ncbi.nlm.nih.gov/pubmed/12186901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9176-9185.2002
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