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Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
The CD1d reactive glycolipid, α-galactosylceramide (α-GalCer), potently activates T cell receptor-α type I invariant NKT cells that secondarily stimulate the proliferation and activation of other leukocytes, including NK cells. Here we report a rational approach to improving the antitumor activity o...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1364507/ https://ncbi.nlm.nih.gov/pubmed/15967825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042280 |
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