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5′-Long Terminal Repeat-Selective CpG Methylation of Latent Human T-Cell Leukemia Virus Type 1 Provirus In Vitro and In Vivo

CpG methylation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeat (LTR) has been implicated in proviral latency, but there is presently little information available regarding the pattern of LTR methylation and its effect on viral gene expression. To gain insight into the mechan...

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Main Authors: Koiwa, Tsukasa, Hamano-Usami, Akiko, Ishida, Takaomi, Okayama, Akihiko, Yamaguchi, Kazunari, Kamihira, Shimeru, Watanabe, Toshiki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136445/
https://ncbi.nlm.nih.gov/pubmed/12186921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9389-9397.2002
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