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The Antiviral Efficacy of the Murine Alpha-1 Interferon Transgene against Ocular Herpes Simplex Virus Type 1 Requires the Presence of CD4(+), α/β T-Cell Receptor-Positive T Lymphocytes with the Capacity To Produce Gamma Interferon

Alpha/beta interferons (IFN-α/βs) are known to antagonize herpes simplex virus type 1 (HSV-1) infection by directly blocking viral replication and promoting additional innate and adaptive, antiviral immune responses. To further define the relationship between the adaptive immune response and IFN-α/β...

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Detalhes bibliográficos
Main Authors: Carr, Daniel J. J., Noisakran, Sansanee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136437/
https://ncbi.nlm.nih.gov/pubmed/12186922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9398-9406.2002
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