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Human monoclonal antibodies encoded by the V4-34 gene segment show cold agglutinin activity and variable multireactivity which correlates with the predicted charge of the heavy-chain variable region.

We have characterized the reactivities of a panel of V4-34-encoded human IgM monoclonal antibodies (mAb) which bind the erythrocyte Rh D antigen, derived from an immunized individual. These were compared with the specificities of V4-34-encoded autoantibodies with I/i reactivity produced from patient...

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Bibliografiska uppgifter
Huvudupphovsmän: Thorpe, S J, Turner, C E, Stevenson, F K, Spellerberg, M B, Thorpe, R, Natvig, J B, Thompson, K M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364116/
https://ncbi.nlm.nih.gov/pubmed/9536129
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