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Apoptosis with FasL+ cell infiltration in the periphery and thymus of corrected autoimmune mice.

Fas (CD95) ligand (L) is a death factor that binds to its receptor, Fas, and induces apoptotic cell death, a crucial process in immunological tolerance. gld (generalized lymphoproliferative disorder) mice, which have a point mutation in the FasL gene, develop spontaneous systemic autoimmune syndrome...

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Detalhes bibliográficos
Main Authors: Kobata, T, Takasaki, K, Asahara, H, Hong, N M, Masuko-Hongo, K, Kato, T, Hirose, S, Shirai, T, Kayagaki, N, Yagita, H, Okumura, K, Nishioka, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364060/
https://ncbi.nlm.nih.gov/pubmed/9415028
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