HIV-1-specific cell-mediated immune responses induced by DNA vaccination were enhanced by mannan-coated liposomes and inhibited by anti-interferon-gamma antibody.

The adjuvant effect of mannan-coated liposomes on human immunodeficiency virus type-1 (HIV-1) DNA vaccine and the mechanism of this enhancement were studied. Coating of cationic liposomes with mannan significantly enhanced the ability of this vaccine to induce an HIV-specific delayed-type hypersensi...

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Détails bibliographiques
Auteurs principaux: Toda, S, Ishii, N, Okada, E, Kusakabe, K I, Arai, H, Hamajima, K, Gorai, I, Nishioka, K, Okuda, K
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1363989/
https://ncbi.nlm.nih.gov/pubmed/9370932
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