p56lck is not essential for the T-cell response to allo-MHC antigens.

In mice lacking the src family protein tyrosine kinase, p 56lck (lck -/-), a greatly reduced number of peripheral T cells is observed due to a profound blockage of the thymocyte development. The peripheral T cells in lck -/- mice exhibit proliferative response after T-cell receptor (TCR)-crosslinkin...

Full description

Saved in:
Bibliographic Details
Main Authors: Yamada, H, Kong, Y Y, Kishihara, K, Mak, T W, Nomoto, K
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1363978/
https://ncbi.nlm.nih.gov/pubmed/9370921
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items