Pharmacological Cyclin-Dependent Kinase Inhibitors Inhibit Replication of Wild-Type and Drug-Resistant Strains of Herpes Simplex Virus and Human Immunodeficiency Virus Type 1 by Targeting Cellular, Not Viral, Proteins

Pharmacological cyclin-dependent kinase (cdk) inhibitors (PCIs) block replication of several viruses, including herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1). Yet, these antiviral effects could result from inhibition of either cellular cdks or viral enzymes. For...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Schang, Luis M., Bantly, Andrew, Knockaert, Marie, Shaheen, Farida, Meijer, Laurent, Malim, Michael H., Gray, Nathanael S., Schaffer, Priscilla A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Vaccines and Antiviral Agents
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136397/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12097601/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.15.7874-7882.2002
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