A step-wise expansion of intestinal intraepithelial T lymphocytes in association with microbial colonization is defined by sensitivity to cyclosporin A.

Murine intestinal intraepithelial lymphocytes (IELs) consist of T cells bearing alpha beta-antigen receptor (alpha beta-IELs) and those bearing gamma delta-IELs). Although gamma delta-IELs outnumber alpha beta-IELs in germ-free (GF) mice, oral inoculation of fecal suspension from conventional (CV) m...

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Bibliographic Details
Main Authors: Kawaguchi-Miyashita, M, Nanno, M, Shimada, S, Nagaoka, N, Okada, Y, Matsumoto, S, Umesaki, Y, Matsuoka, Y, Ohwaki, M
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1363886/
https://ncbi.nlm.nih.gov/pubmed/9378505
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