The EBNA2 Polyproline Region Is Dispensable for Epstein-Barr Virus-Mediated Immortalization Maintenance

Epstein-Barr virus nuclear antigen 2 (EBNA2) is required for EBV-mediated immortalization of primary human B cells and is a direct transcriptional activator of viral and cellular genes. The prototype EBNA2 protein contains a unique motif in which 43 out of 45 amino acids are prolines (polyproline re...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Gordadze, Alexey V., Poston, David, Ling, Paul D.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Virus-Cell Interactions
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.14.7349-7355.2002
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