Highly Pathogenic Simian Immunodeficiency Virus mne Variants That Emerge during the Course of Infection Evolve Enhanced Infectivity and the Ability To Downregulate CD4 but Not Class I Major Histocompatibility Complex Antigens

The replicative, cytopathic, and antigenic properties of simian immunodeficiency virus (SIV) variants influence its replication efficiency in vivo. To further define the viral properties and determinants that may be important for high-level replication in vivo and progression to AIDS, we compared a...

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izdano v:	J Virol
Principais autores:	Patel, Parul G., Yu Kimata, Monica T., Biggins, Julia E., Wilson, Joelle M., Kimata, Jason T.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Pathogenesis and Immunity
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136284/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12050354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.13.6425-6434.2002
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