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Fatty Acid Modification of the Coxsackievirus and Adenovirus Receptor

Membrane-proximal cysteines 259 and 260 in the cytoplasmic tail of the coxsackievirus and adenovirus receptor (CAR) are known to be essential for the tumor suppression activity of CAR. We demonstrate that these residues provide an S-acylation motif for modification of CAR with the fatty acid palmita...

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Bibliografiske detaljer
Main Authors: van"t Hof, Wouter, Crystal, Ronald G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136239/
https://ncbi.nlm.nih.gov/pubmed/12021372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.12.6382-6386.2002
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