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Mechanism of Virulence Attenuation of Glycosaminoglycan-Binding Variants of Japanese Encephalitis Virus and Murray Valley Encephalitis Virus

The in vivo mechanism for virulence attenuation of laboratory-derived variants of two flaviviruses in the Japanese encephalitis virus (JEV) serocomplex is described. Host cell adaptation of JEV and Murray Valley encephalitis virus (MVE) by serial passage in adenocarcinoma cells selected for variants...

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Bibliografiske detaljer
Main Authors: Lee, Eva, Lobigs, Mario
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136177/
https://ncbi.nlm.nih.gov/pubmed/11967307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.4901-4911.2002
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