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Replication Fidelity of the supF Gene Integrated in the Thymidine Kinase Locus of Herpes Simplex Virus Type 1

Recombinant viruses were constructed to have an Escherichia coli replicon containing a mutagenesis marker, the supF gene, integrated within the thymidine kinase locus (tk) of herpes simplex virus type 1. These viruses expressed either wild-type or mutant DNA polymerase (Pol) and were tested in a mut...

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Udgivet i:J Virol
Principais autores: Hwang, Ying T., Liu, Bu-Yuan, Hwang, Charles B. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136086/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11907200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.8.3605-3614.2002
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