Transcriptional Targeting of Lentiviral Vectors by Long Terminal Repeat Enhancer Replacement

Gene therapy of many genetic diseases requires permanent gene transfer into self-renewing stem cells and restriction of transgene expression to specific progenies. Human immunodeficiency virus (HIV)-derived lentiviral vectors are very effective in transducing rare, nondividing stem cell populations...

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Detalhes bibliográficos
Main Authors: Lotti, Francesco, Menguzzato, Emilio, Rossi, Claudia, Naldini, Luigi, Ailles, Laurie, Mavilio, Fulvio, Ferrari, Giuliana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136069/
https://ncbi.nlm.nih.gov/pubmed/11907239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.8.3996-4007.2002
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