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Serpina1 is a potent inhibitor of IL-8-induced hematopoietic stem cell mobilization

Here, we report that cytokine-induced (granulocyte colony-stimulating factor and IL-8) hematopoietic stem cell (HSC) and hematopoietic progenitor cell (HPC) mobilization is completely inhibited after low-dose (0.5 Gy) total-body irradiation (TBI). Because neutrophil granular proteases are regulatory...

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Detalhes bibliográficos
Main Authors: van Pel, Melissa, van Os, Ronald, Velders, Gerjo A., Hagoort, Henny, Heegaard, Peter M. H., Lindley, Ivan J. D., Willemze, Roel, Fibbe, Willem E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360568/
https://ncbi.nlm.nih.gov/pubmed/16432201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510192103
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