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Novel Swine Virulence Determinant in the Left Variable Region of the African Swine Fever Virus Genome

Previously we have shown that the African swine fever virus (ASFV) NL gene deletion mutant E70ΔNL is attenuated in pigs. Our recent observations that NL gene deletion mutants of two additional pathogenic ASFV isolates, Malawi Lil-20/1 and Pr4, remained highly virulent in swine (100% mortality) sugge...

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Udgivet i:J Virol
Principais autores: Neilan, J. G., Zsak, L., Lu, Z., Kutish, G. F., Afonso, C. L., Rock, D. L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136047/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11884534/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.7.3095-3104.2002
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