Pathogenesis of B-Cell Superantigen-Induced Immune Complex-Mediated Inflammation

Staphylococcal protein A (SpA) is representative of a new class of antigens, the B-cell superantigens (SAgs). These antigens bind to the Fab regions of immunoglobulin molecules outside their complementarity-determining regions. SpA, the best-studied B-cell SAg, reacts with the Fabs of most V(H)3(+)...

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Detalhes bibliográficos
Main Authors: Anderson, Amy L., Sporici, Romeo, Lambris, John, LaRosa, David, Levinson, Arnold I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360360/
https://ncbi.nlm.nih.gov/pubmed/16428769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1196-1203.2006
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