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Toll-Like Receptor 4 Protects against Lethal Leptospira interrogans Serovar Icterohaemorrhagiae Infection and Contributes to In Vivo Control of Leptospiral Burden

The roles of innate immune responses in protection from or pathogenesis of severe leptospirosis remain unclear. We examined the role of Toll-like receptors (TLRs) in mouse infection and macrophage responses to Leptospira. C3H/HeJ mice (TLR4 deficient) and C3H/HeJ-SCID mice, but not C3H/OuJ mice (TLR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Viriyakosol, Suganya, Matthias, Michael A., Swancutt, Mark A., Kirkland, Theo N., Vinetz, Joseph M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360355/
https://ncbi.nlm.nih.gov/pubmed/16428731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.887-895.2006
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