Phenotypic Switching in a Cryptococcus neoformans Variety gattii Strain Is Associated with Changes in Virulence and Promotes Dissemination to the Central Nervous System

This is the first report of a Cryptococcus neoformans var. gattii strain (serotype B) that switches reversibly between its parent mucoid (NP1-MC) colony morphology and a smooth (NP1-SM) colony morphology. Similar to C. neoformans var. grubii and C. neoformans var. neoformans strains, the switch is a...

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Bibliographic Details
Main Authors: Jain, N., Li, Li, McFadden, D. C., Banarjee, U., Wang, X., Cook, E., Fries, B. C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360350/
https://ncbi.nlm.nih.gov/pubmed/16428732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.896-903.2006
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