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Predictors of High Ethanol Consumption in RIIβ Knock-Out Mice: Assessment of Anxiety and Ethanol-Induced Sedation

BACKGROUND: Genetic and pharmacological evidence suggests that the cyclic adenosine monophosphate–dependent protein kinase A pathway modulates neurobiological responses to ethanol. Mutant mice lacking the RIIβ subunit of protein kinase A (RIIβ(−/−)) are resistant to ethanol-induced sedation and drin...

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Detalhes bibliográficos
Main Authors: Fee, Jon R., Sparta, Dennis R., Knapp, Darin J., Breese, George R., Picker, Mitchell J., Thiele, Todd E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360241/
https://ncbi.nlm.nih.gov/pubmed/15597077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.ALC.0000141809.53115.71
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