A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames

CTL based vaccine strategies in the macaque model of AIDS have shown promise in slowing the progression to disease. However, rapid CTL escape viruses can emerge rendering such vaccination useless. We hypothesized that such escape is made more difficult if the immunizing CTL epitope falls within a re...

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Detalhes bibliográficos
Main Authors: Klase, Zachary, Donio, Michael J, Blauvelt, Andrew, Marx, Preston A, Jeang, Kuan-Teh, Smith, Stephen M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360091/
https://ncbi.nlm.nih.gov/pubmed/16398928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-1
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