A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames

CTL based vaccine strategies in the macaque model of AIDS have shown promise in slowing the progression to disease. However, rapid CTL escape viruses can emerge rendering such vaccination useless. We hypothesized that such escape is made more difficult if the immunizing CTL epitope falls within a re...

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Main Authors: Klase, Zachary, Donio, Michael J, Blauvelt, Andrew, Marx, Preston A, Jeang, Kuan-Teh, Smith, Stephen M
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2006
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360091/
https://ncbi.nlm.nih.gov/pubmed/16398928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-1
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