High-Level Primary CD8(+) T-Cell Response to Human Immunodeficiency Virus Type 1 Gag and Env Generated by Vaccination with Recombinant Vesicular Stomatitis Viruses

We investigated the primary cellular immune responses to human immunodeficiency virus type 1 (HIV-1) Env and Gag proteins elicited by recombinant vesicular stomatitis viruses (rVSVs). The primary response to Env peaked 5 to 7 days after intraperitoneal vaccination, at which time 40% of CD8(+) cells...

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Main Authors: Haglund, Karl, Leiner, Ingrid, Kerksiek, Kristen, Buonocore, Linda, Pamer, Eric, Rose, John K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC136000/
https://ncbi.nlm.nih.gov/pubmed/11861840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2730-2738.2002
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