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Specific Inactivation of Inhibitory Sequences in the 5′ End of the Human Papillomavirus Type 16 L1 Open Reading Frame Results in Production of High Levels of L1 Protein in Human Epithelial Cells

The expression of human papillomavirus type 16 late genes encoding virus capsid proteins L1 and L2 is restricted to terminally differentiated epithelial cells in the superficial layers of the squamous epithelium. We wish to understand the molecular mechanisms that determine the levels of expression...

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Detalhes bibliográficos
Main Authors: Collier, Brian, Öberg, Daniel, Zhao, Xiaomin, Schwartz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135970/
https://ncbi.nlm.nih.gov/pubmed/11861841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2739-2752.2002
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