Evolution of a Human Immunodeficiency Virus Type 1 Variant with Enhanced Replication in Pig-Tailed Macaque Cells by DNA Shuffling

DNA shuffling facilitated the evolution of a human immunodeficiency virus type 1 (HIV-1) variant with enhanced replication in pig-tailed macaque peripheral blood mononuclear cells (pt mPBMC). This variant consists exclusively of HIV-1-derived sequences with the exception of simian immunodeficiency v...

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Main Authors: Pekrun, Katja, Shibata, Riri, Igarashi, Tatsuhiko, Reed, Margaret, Sheppard, Liana, Patten, Philip A., Stemmer, Willem P. C., Martin, Malcolm A., Soong, Nay-Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Virus-Cell Interactions
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC135969/
https://ncbi.nlm.nih.gov/pubmed/11861859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.2924-2935.2002
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