Targeting Adenoviral Vectors by Using the Extracellular Domain of the Coxsackie-Adenovirus Receptor: Improved Potency via Trimerization

Adenovirus binds to mammalian cells via interaction of fiber with the coxsackie-adenovirus receptor (CAR). Redirecting adenoviral vectors to enter target cells via new receptors has the advantage of increasing the efficiency of gene delivery and reducing nonspecific transduction of untargeted tissue...

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में प्रकाशित:	J Virol
मुख्य लेखकों:	Kim, Jin, Smith,*, Theodore, Idamakanti, Neeraja, Mulgrew, Kathy, Kaloss, Michele, Kylefjord, Helen, Ryan, Patricia C., Kaleko, Michael, Stevenson, Susan C.
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology (ASM) 2002
विषय:	Gene Therapy
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.1892-1903.2002
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