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The Initiator Element in a Herpes Simplex Virus Type 1 Late-Gene Promoter Enhances Activation by ICP4, Resulting in Abundant Late-Gene Expression

The start site regions of late genes of herpes simplex virus type 1 are similar to the eukaryotic initiator sequence (Inr), have been shown to affect the levels of expression, and may also play a role in transcription activation by the viral activator ICP4. A series of linker-scanning mutations span...

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Autors principals: Kim, Dool-Bboon, Zabierowski, Susan, DeLuca, Neal A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135907/
https://ncbi.nlm.nih.gov/pubmed/11799149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.4.1548-1558.2002
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