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Administration of Recombinant Rhesus Interleukin-12 during Acute Simian Immunodeficiency Virus (SIV) Infection Leads to Decreased Viral Loads Associated with Prolonged Survival in SIVmac251-Infected Rhesus Macaques

The ability of recombinant rhesus interleukin-12 (rMamu-IL-12) administration during acute simian immunodeficiency virus SIVmac251 infection to influence the quality of the antiviral immune responses was assessed in rhesus macaques. Group I (n = 4) was the virus-only control group. Group II and III...

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Published in:J Virol
Main Authors: Ansari, A. A., Mayne, A. E., Sundstrom, J. B., Bostik, P., Grimm, B., Altman, J. D., Villinger, F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2002
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11799168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.4.1731-1743.2002
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