Interleukin-2 induces early multisystem organ edema mediated by neutrophils.

Interleukin-2 (IL-2), an agent known to activate neutrophils (PMN) with thromboxane (Tx)B2 release, produces pulmonary edema within 6 hours of intravenous infusion. This study tests the role of PMN in mediating the edema. Anesthetized rats received 10(6)U recombinant human IL-2 (n = 15) or vehicle (...

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Autors principals: Welbourn, R, Goldman, G, Kobzik, L, Paterson, I, Shepro, D, Hechtman, H B
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1358518/
https://ncbi.nlm.nih.gov/pubmed/1867524
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