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Lovastatin inhibits gallstone formation in the cholesterol-fed prairie dog.

The efficacy of lovastatin, an inhibitor of hepatic cholesterol synthesis in the prevention of cholesterol gallstone formation, was evaluated in the prairie dog model. Two groups of animals were maintained on either nonlithogenic or 1.2% cholesterol-enriched chow for 21 days. Seven of the animals in...

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Detalhes bibliográficos
Main Authors: Saunders, K D, Cates, J A, Abedin, M Z, Rege, S, Festekdjian, S F, Howard, W, Roslyn, J J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1358514/
https://ncbi.nlm.nih.gov/pubmed/1867522
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