Mucosal Immunization of Rhesus Monkeys against Respiratory Syncytial Virus Subgroups A and B and Human Parainfluenza Virus Type 3 by Using a Live cDNA-Derived Vaccine Based on a Host Range-Attenuated Bovine Parainfluenza Virus Type 3 Vector Backbone

Reverse genetics was used to develop a two-component, trivalent live attenuated vaccine against human parainfluenza virus type 3 (HPIV3) and respiratory syncytial virus (RSV) subgroups A and B. The backbone for each of the two components of this vaccine was the attenuated recombinant bovine/human PI...

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Autors principals: Schmidt, Alexander C., Wenzke, Daniel R., McAuliffe, Josephine M., St. Claire, Marisa, Elkins, William R., Murphy, Brian R., Collins, Peter L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135799/
https://ncbi.nlm.nih.gov/pubmed/11773385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1089-1099.2002
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