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Replication of Subgenomic Hepatitis A Virus RNAs Expressing Firefly Luciferase Is Enhanced by Mutations Associated with Adaptation of Virus to Growth in Cultured Cells

Replication of hepatitis A virus (HAV) in cultured cells is inefficient and difficult to study due to its protracted and generally noncytopathic cycle. To gain a better understanding of the mechanisms involved, we constructed a subgenomic HAV replicon by replacing most of the P1 capsid-coding sequen...

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Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Yi, MinKyung, Lemon, Stanley M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135777/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773393/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.3.1171-1180.2002
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