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Statistical significance of clusters of motifs represented by position specific scoring matrices in nucleotide sequences

The human genome encodes the transcriptional control of its genes in clusters of cis-elements that constitute enhancers, silencers and promoter signals. The sequence motifs of individual cis- elements are usually too short and degenerate for confident detection. In most cases, the requirements for o...

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Autores principales: Frith, Martin C., Spouge, John L., Hansen, Ulla, Weng, Zhiping
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC135758/
https://ncbi.nlm.nih.gov/pubmed/12136103
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