RNase H Activity Is Required for High-Frequency Repeat Deletion during Moloney Murine Leukemia Virus Replication

It has been postulated that retroviral recombination, like strong stop template switching, requires the RNase H activity of reverse transcriptase. To address this hypothesis, Moloney murine leukemia virus-based vectors, which were designed to test the recombination-related property of direct repeat...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Brincat, Jennifer L., Pfeiffer, Julie K., Telesnitsky, Alice
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Recombination and Evolution
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11739674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.1.88-95.2002
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