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RNase H Activity Is Required for High-Frequency Repeat Deletion during Moloney Murine Leukemia Virus Replication

It has been postulated that retroviral recombination, like strong stop template switching, requires the RNase H activity of reverse transcriptase. To address this hypothesis, Moloney murine leukemia virus-based vectors, which were designed to test the recombination-related property of direct repeat...

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Detalhes bibliográficos
Main Authors: Brincat, Jennifer L., Pfeiffer, Julie K., Telesnitsky, Alice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135712/
https://ncbi.nlm.nih.gov/pubmed/11739674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.1.88-95.2002
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